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Jun, 2018
关注交叉模态抗原表位预测
Attentive cross-modal paratope prediction
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Andreea Deac, Petar Veličković, Pietro Sormanni
TL;DR
本研究利用深度神经网络实现抗体重要区域的预测，与先前的物理模型相比，Parapred取得了更好的表现，其计算效率得到了显著提高，同时，实现交叉模态注意力，抗体残基与抗原残基相互关注，取得了新的最佳结果和有意义的解释。
Abstract
antibodies
are a critical part of the
immune system
, having the function of directly neutralising or tagging undesirable objects (the antigens) for future destruction. Being able to predict which amino acids belo
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