Lesion segmentation is an important problem in computer-assisted diagnosis that remains challenging due to the prevalence of low contrast, irregular boundaries that are unamenable to shape priors. We introduce Deep Active Lesion Segmentation (DALS), a fully automated segmentation framework for that leverages the powerful nonlinear feature extraction abilities of fully Convolutional Neural Networks (CNNs) and the precise boundary delineation abilities of Active Contour Models (ACMs). Our DALS framework benefits from an improved level-set ACM formulation with a per-pixel-parameterized energy functional and a novel multiscale encoder-decoder CNN that learns an initialization probability map along with parameter maps for the ACM. We evaluate our lesion segmentation model on a new Multiorgan Lesion Segmentation (MLS) dataset that contains images of various organs, including brain, liver, and lung, across different imaging modalities---MR and CT. Our results demonstrate favorable performance compared to competing methods, especially for small training datasets.

本文提出了一种基于 Convolutional Neural Networks 和 Active Contour Models 的 Deep Active Lesion Segmentation (DALS) 框架用于器官病变分割，该框架在新的 Multiorgan Lesion Segmentation (MLS) 数据集上取得了比竞争方法更好的性能。

深度主动损伤分割