It is explored how physicalist mereotopology and Peircean semiotics can be applied to represent models, simulations, and workflows in multiscale modelling and simulation of physical systems within a top-level ontology. It is argued that to conceptualize modelling and simulation in such a framework, two major types of semiosis need to be formalized and combined with each other: Interpretation, where a sign and a represented object yield an interpretant (another representamen for the same object), and metonymization, where the represented object and a sign are in a three-way relationship with another object to which the signification is transferred. It is outlined how the main elements of the pre-existing simulation workflow descriptions MODA and OSMO, i.e., use cases, models, solvers, and processors, can be aligned with a top-level ontology that implements this ontological paradigm, which is here referred to as mereosemiotic physicalism. Implications are discussed for the development of the European Materials and Modelling Ontology, an implementation of mereosemiotic physicalism.

探讨将基于EMMO范例的顶层本体论应用于物理系统模型及其在计算工程实践中的应用，比较了多种实现方式，并描述了这种范例下可能的顶层本体论类型的设计空间。

基于欧洲材料和建模本体论的语义互操作性及其本体论范式：Mereosemiotics