The current study of cell architecture of inflammation in histopathology images commonly performed for diagnosis and research purposes excludes a lot of information available on the biopsy slide. In autoimmune diseases, major outstanding research questions remain regarding which cell types participate in inflammation at the tissue level,and how they interact with each other. While these questions can be partially answered using traditional methods, artificial intelligence approaches for segmentation and classification provide a much more efficient method to understand the architecture of inflammation in autoimmune disease, holding a great promise for novel insights. In this paper, we empirically develop deep learning approaches that uses dermatomyositis biopsies of human tissue to detect and identify inflammatory cells. Our approach improves classification performance by 26% and segmentation performance by 5%. We also propose a novel post-processing autoencoder architecture that improves segmentation performance by an additional 3%. We have open-sourced our approach and architecture at https://github.com/pranavsinghps1/DEDL

该论文中介绍了一种利用深度学习方法对人体组织进行皮肤肌炎活检的细胞自动分类和分割的方法，在细胞分类和分割方面的表现均有所提升，该方法对研究自身免疫性疾病的细胞组成有着可靠的应用前景。

一种数据高效的深度学习框架，用于组织病理学图像的分割和分类