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Apr, 2024
蛋白质性质的不确定性预测
Protein property prediction with uncertainties
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Peter Mørch Groth, Mads Herbert Kerrn, Lars Olsen, Jesper Salomon, Wouter Boomsma
TL;DR
在蛋白质领域，可靠的变异影响预测取得了显著进展，通过提供具备不确定性估计的高斯过程回归模型Kermut，能够在蛋白质属性预测中获得最先进的性能，并展示了对预测的可靠性定量估计的质量评估结果。
Abstract
Reliable
prediction
of
variant effects
in
proteins
has seen considerable progress in recent years. The increasing availability of data in
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