Advances in large language models (LLMs) have encouraged their adoption in
the healthcare domain where vital clinical information is often contained in
unstructured notes. Cancer staging status is available in clinical reports, but
it requires natural language processing to extract the status from the
unstructured text. With the advance in clinical-oriented LLMs, it is promising
to extract such status without extensive efforts in training the algorithms.
Prompting approaches of the pre-trained LLMs that elicit a model's reasoning
process, such as chain-of-thought, may help to improve the trustworthiness of
the generated responses. Using self-consistency further improves model
performance, but often results in inconsistent generations across the multiple
reasoning paths. In this study, we propose an ensemble reasoning approach with
the aim of improving the consistency of the model generations. Using an open
access clinical large language model to determine the pathologic cancer stage
from real-world pathology reports, we show that the ensemble reasoning approach
is able to improve both the consistency and performance of the LLM in
determining cancer stage, thereby demonstrating the potential to use these
models in clinical or other domains where reliability and trustworthiness are
critical.

通过使用开放式临床大型语言模型从实际病理报告中确定病理癌症分期，我们提出了一种集成推理方法，以改善模型生成的一致性和性能，从而展示了在可靠性和可信度至关重要的临床或其他领域中使用这些模型的潜力。