Biomedical documents such as Electronic Health Records (EHRs) contain a large
amount of information in an unstructured format. The data in EHRs is a hugely
valuable resource documenting clinical narratives and decisions, but whilst the
text can be easily understood by human doctors it is challenging to use in
research and clinical applications. To uncover the potential of biomedical
documents we need to extract and structure the information they contain. The
task at hand is Named Entity Recognition and Linking (NER+L). The number of
entities, ambiguity of words, overlapping and nesting make the biomedical area
significantly more difficult than many others. To overcome these difficulties,
we have developed the Medical Concept Annotation Tool (MedCAT), an open-source
unsupervised approach to NER+L. MedCAT uses unsupervised machine learning to
disambiguate entities. It was validated on MIMIC-III (a freely accessible
critical care database) and MedMentions (Biomedical papers annotated with
mentions from the Unified Medical Language System). In case of NER+L, the
comparison with existing tools shows that MedCAT improves the previous best
with only unsupervised learning (F1=0.848 vs 0.691 for disease detection;
F1=0.710 vs. 0.222 for general concept detection). A qualitative analysis of
the vector embeddings learnt by MedCAT shows that it captures latent medical
knowledge available in EHRs (MIMIC-III). Unsupervised learning can improve the
performance of large scale entity extraction, but it has some limitations when
working with only a couple of entities and a small dataset. In that case
options are supervised learning or active learning, both of which are supported
in MedCAT via the MedCATtrainer extension. Our approach can detect and link
millions of different biomedical concepts with state-of-the-art performance,
whilst being lightweight, fast and easy to use.

该论文提出了一种基于无监督机器学习的医疗概念注释工具 MedCAT，可在不需要人工标注数据的情况下从电子病历等医疗文档中提取并链接具有潜在医疗知识的实体，表现出良好的性能，是一种轻量级、快速且易于使用的工具。