The problem of finding itemsets that are statistically significantly enriched
in a class of transactions is complicated by the need to correct for multiple
hypothesis testing. Pruning untestable hypotheses was recently proposed as a
strategy for this task of significant itemset mining. It was shown to lead to
greater statistical power, the discovery of more truly significant itemsets,
than the standard Bonferroni correction on real-world datasets. An open
question, however, is whether this strategy of excluding untestable hypotheses
also leads to greater statistical power in subgraph mining, in which the number
of hypotheses is much larger than in itemset mining. Here we answer this
question by an empirical investigation on eight popular graph benchmark
datasets. We propose a new efficient search strategy, which always returns the
same solution as the state-of-the-art approach and is approximately two orders
of magnitude faster. Moreover, we exploit the dependence between subgraphs by
considering the effective number of tests and thereby further increase the
statistical power.

通过对八个流行图形基准数据集进行实证调查，本文回答了一个开放性问题，即排除无法测试的假设是否也会提高子图挖掘的统计功率，并提出了一种新的高效搜索策略，极大地提高了统计功率。