Graph neural networks (GNNs) are becoming increasingly popular in the medical domain for the tasks of disease classification and outcome prediction. Since patient data is not readily available as a graph, most existing methods either manually define a patient graph, or learn a latent graph based on pairwise similarities between the patients. There are also hypergraph neural network (HGNN)-based methods that were introduced recently to exploit potential higher order associations between the patients by representing them as a hypergraph. In this work, we propose a patient hypergraph network (PHGN), which has been investigated in an inductive learning setup for binary outcome prediction in oropharyngeal cancer (OPC) patients using computed tomography (CT)-based radiomic features for the first time. Additionally, the proposed model was extended to perform time-to-event analyses, and compared with GNN and baseline linear models.

本文首次提出了病患超图网络（PHGN），并在感染舌咽癌（OPC）患者的计算机断层扫描（CT）辐射组学特征上进行了针对二分类和时间分析的研究，与图神经网络和基准线性模型进行了比较。

口咽癌患者预测结果的图数据建模