Breast cancer is the most frequently diagnosed cancer and leading cause of
cancer-related death among females worldwide. In this article, we investigate
the applicability of densely connected convolutional neural networks to the
problems of histology image classification and whole slide image segmentation
in the area of computer-aided diagnoses for breast cancer. To this end, we
study various approaches for transfer learning and apply them to the data set
from the 2018 grand challenge on breast cancer histology images (BACH).

探讨利用密集连接卷积神经网络进行乳腺癌计算机辅助诊断中的组织学图像分类和全扫描图像分割的可行性。采用迁移学习，应用于 2018 年乳腺癌组织学图像大挑战的数据集，并研究不同方法。

使用密集连接卷积网络评估乳腺癌组织学

Assessment of Breast Cancer Histology using Densely Connected  Convolutional Networks

Breast cancer is one of the main causes of cancer death worldwide. Early
diagnostics significantly increases the chances of correct treatment and
survival, but this process is tedious and often leads to a disagreement between
pathologists. Computer-aided diagnosis systems showed potential for improving
the diagnostic accuracy. In this work, we develop the computational approach
based on deep convolution neural networks for breast cancer histology image
classification. Hematoxylin and eosin stained breast histology microscopy image
dataset is provided as a part of the ICIAR 2018 Grand Challenge on Breast
Cancer Histology Images. Our approach utilizes several deep neural network
architectures and gradient boosted trees classifier. For 4-class classification
task, we report 87.2% accuracy. For 2-class classification task to detect
carcinomas we report 93.8% accuracy, AUC 97.3%, and sensitivity/specificity
96.5/88.0% at the high-sensitivity operating point. To our knowledge, this
approach outperforms other common methods in automated histopathological image
classification. The source code for our approach is made publicly available at
this https URL

本研究基于深度卷积神经网络开发了计算方法，用于乳腺癌组织病理图像分类，包括四类和两类（用于检测癌变）分类任务，在高灵敏度操作点上，我们报告了 93.8% 的准确性，97.3% 的 AUC 和 96.5/88.0% 的敏感性 / 特异性，超过了其他常见的自动组织病理学图像分类方法。