TL;DR使用 Vector Field Network (VFN) 方法,能够高效地对蛋白质扩散和设计进行建模,此方法在蛋白质向量计算以及帧与原子建模方面,表现出优于其他现有方法的性能。
Abstract
Innovations like protein diffusion have enabled significant progress in de
novo protein design, which is a vital topic in life science. These methods
typically depend on protein structure encoders to model residue backbone
frames, where atoms do not exist. Most prior encoders rely on a